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ZOSTAVAX in Persons Imminently Receiving Chemotherapy for Solid Organ Tumors

Shingles Clinical Trial

Official title:
A Pilot Study Using a Randomized Design to Evaluate the Immunologic Efficacy and Safety of ZOSTAVAX in Persons Imminently Receiving Chemotherapy for Solid Organ Tumors

Clinical Trial Summary

This study evaluates if the shingles vaccine works in those persons that receive it before they receive chemotherapy for solid organ tumors. Half of the participants will receive the ZOSTAVAX shingle vaccine and half of the participants will not received anything.

Clinical Trial Description

This study is a single blind randomized clinical trial measuring the immunologic efficacy of ZOSTAVAX vs. no vaccine in 60 adults with solid organ tumors before, during and after chemotherapy. The personnel performing the laboratory studies will be blinded to vaccine vs. no vaccine. In a pilot study of an FDA approved vaccine that is being used within the parameters of the package insert and ACIP recommendations, placebo vaccine is not required to access our key primary immunologic endpoint. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02444936
Study type Interventional
Source Louis Stokes VA Medical Center
Contact
Status Active, not recruiting
Phase Phase 4
Start date May 1, 2015
Completion date May 1, 2018
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