Clinical Trials Logo
  1. Home
  2. Sexually Transmitted Diseases
  3. NCT04553068

Evaluation of EVO100 for Prevention of Urogenital Chlamydia Trachomatis and Neisseria Gonorrhoeae Infection — EVOGUARD  

Sexually Transmitted Diseases Clinical Trial

Official title:
Phase 3 Double-blind Placebo-controlled Efficacy Trial of EVO100 Vaginal Gel for the Prevention of Urogenital Chlamydia Trachomatis and Neisseria Gonorrhoeae Infection

Clinical Trial Summary

This study will evaluate whether EVO100 vaginal gel prevents the sexual transmission of CT and GC infection

Clinical Trial Description

In this phase 3 double blind placebo controlled, efficacy study, women who have had a urogenital chlamydia or gonorrhea infection at any time over the 16 weeks preceding the enrollment Visit with one or more risk factors, or found to be positive for either infection at Screening Visit with one or more risk factors will be enrolled. After a screening period of up to 35 days, women will be randomized to receive either EVO100 vaginal gel or placebo. Each woman will participate in the study until she has completed 16 weeks of study medication or observation or tests positive for CT or GC infection. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04553068
Study type Interventional
Source Evofem Inc.
Contact
Status Completed
Phase Phase 3
Start date October 15, 2020
Completion date July 28, 2022
View Details
See also
  Status Clinical Trial Phase
Completed NCT02579135 - Reducing HIV Risk Among Adolescents: Evaluating Project HEART N/A
Enrolling by invitation NCT06127277 - Next4You: A Fully Mobile Relationships Based Program for Youth in Foster Care N/A
Recruiting NCT05889689 - Evaluation of an Adolescent Pregnancy Prevention Program; Relationship Smarts+ With Lessons From Mind Matters N/A
Completed NCT02516930 - A Non-inferiority Randomized Controlled Trial to Evaluate Promoting Condom Use Among MSM and Transgender Individuals in China N/A
Completed NCT03063385 - Puerto Rico Cuidalos Parent-adolescent Program N/A
Completed NCT02009046 - Randomized Evaluation of a Multi-Component, Rights-Based Sexuality Education Initiative for High School Students N/A
Completed NCT01411878 - Louisville Teen Pregnancy Prevention Project N/A
Completed NCT01303575 - Internet-Based Sexual Health Education for Middle School Native American Youth N/A
Completed NCT00167505 - All About Youth: Evaluation of Sexual Risk Avoidance and Risk Reduction Programs for Middle School Students N/A
Completed NCT00183456 - A Peer-Oriented HIV Prevention Outreach Program for Individuals at High Risk for HIV and Other STIs Phase 2
Completed NCT00336180 - Adolescent Drug and HIV Prevention in South Africa Phase 2/Phase 3
Completed NCT01084395 - Reducing HIV Risk Among Mexican Youth N/A
Completed NCT00161382 - Development and Evaluation of an HIV, STD, and Pregnancy Prevention Program for Middle School Students N/A
Completed NCT00710060 - Effectiveness of a Community-level HIV/STD Prevention Intervention in Promoting Safer Sexual Behaviors in High-risk Populations Phase 3
Completed NCT00640653 - Efficacy of an Abstinence-Only HIV Risk-Reduction Intervention for Young African-American Adolescents N/A
Completed NCT00289939 - Reducing HIV & Domestic Violence Risk in Women Offenders Phase 3
Completed NCT00137943 - Parents Matter!: Interventions to Promote Effective Parent-Child Communication Phase 1
Completed NCT03408743 - Engineering an Online STI Prevention Program: CSE2 N/A
Completed NCT06104813 - Evaluation of Deaf Men's Knowledge About Sexual Health
Not yet recruiting NCT05910580 - Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years N/A