A Study of Gene Polymorphisms Associated With Specific Presentations of Sexual Addiction

Sexual Addiction Clinical Trial

Official title:

Genetic Markers in Sexual Addiction

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT02844985
• Other study ID #: AFAR 2016-001
• Status: Enrolling by invitation
• Start date: August 17, 2016
• Est. completion date: December 2021

Study information

• Verified date: January 2020
• Source: American Foundation for Addiction Research
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The study is intended to identify gene polymorphisms significantly associated with specific behavioral- and preoccupation-typologies of sexual addiction, and to identify additional potential genetic markers of sexual addiction. Research subjects with sexual addiction will be identified from the out-patient and in-patient populations of the investigative sites. Research subjects in the Control Group will be identified from the general population and from the student body of selected colleges. Approximately 1100 subjects will be enrolled in the study. Anticipating 10% drop-out, this is intended to generate a population of approximately 500 men and women clinically diagnosed with sexual addiction, and approximately 500 healthy men and women who do not meet diagnostic criteria for sexual addiction nor have psychopathology who will serve as the control population.

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 2000
• Est. completion date: December 2021
• Est. primary completion date: June 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Sexual Addict Group

Age >= 18 years

Participating in sexual addiction treatment program

Sexual Addiction Screening Test--Revised (SAST-R) score >= 11

Meets at least 3 diagnostic criteria for sexual addiction

• Control Group

Age >= 18 years

SAST-R score < 6

Exclusion Criteria:

• Sexual Addiction Group

Serious mental illness

Significant cognitive impairment

• Control Group

History of addiction

Current or previous Diagnostic and Statistical Manual (DSM-5) diagnosis

Serious mental illness

Significant cognitive impairment

Related Conditions & MeSH terms

• Behavior, Addictive
• Sexual Addiction

Intervention

Other:
• No Intervention

Locations

Country	Name	City	State
United States	Seattle Christian Counseling	Bellevue	Washington
United States	Pine Grove Behavioral Health and Addiction Services	Hattiesburg	Mississippi
United States	Center for Healthy Sexuality	Houston	Texas
United States	Center for Healthy Sex	Los Angeles	California
United States	Triune Therapy Group	Los Angeles	California
United States	Kavod Center	Rochester	New York
United States	Psychological Counseling Services	Scottsdale	Arizona
United States	Gentle Path at The Meadows	Wickenburg	Arizona

Sponsors (3)

Lead Sponsor	Collaborator
American Foundation for Addiction Research	University of Alberta, University of Southern Mississippi

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Gene polymorphisms identified through polymerase chain reaction using fluorescent primers and restriction fragment length polymorphism analysis		Assessed at Enrollment