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Lactated Ringer Versus Albumin in Early Sepsis Therapy — RASP  

Septic Shock Clinical Trial

Official title:
Ringer Versus Albumin In Septic Patients: a Randomized Controlled Clinical Trial

Clinical Trial Summary

The use of albumin in critical ill patients is a matter of controversy. A large randomized controlled trial reported that albumin was as safe and effective as crystalloid solution for fluid replacement in intensive care unit, although the last one was less expensive. In Surviving Sepsis Campaign International Guidelines there are no preference for crystalloids over colloids. But recently, a retrospective analysis of patients with severe sepsis from SAFE study reported that the use of albumin in these patients would be superior, regarding reduction of mortality. The aim of this study is determine whether the use of albumin improve clinical outcomes in patients with severe sepsis or septic shock.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01337934
Study type Interventional
Source University of Sao Paulo
Contact
Status Completed
Phase Phase 3
Start date October 2013
Completion date December 2017
View Details
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