VTE Incidence in Severe Sepsis and Septic Shock

Severe Sepsis With Septic Shock Clinical Trial

Official title: VTE Incidence and Risk Factors in Patients With Severe Sepsis and Septic Shock

Status Completed

Clinical Trial Summary

Prospective studies on the incidence of VTE during severe sepsis and septic shock remain absent, hindering efficacy assessments regarding current VTE prevention strategies in septic patients. The investigators will prospectively study consecutively enrolled ICU patients with severe sepsis and septic shock admitted at three hospitals. All patients will provide informed consent and the study will be IRB approved. VTE thromboprophylaxis, provided per standard of care and according to the patients' primary team, will be recorded for all patients. Patients will undergo bilateral lower (and upper, if a central venous catheter [CVC] was present) comprehensive compression ultrasonography (CUS) and will be followed for symptomatic deep vein thrombosis (DVT) and pulmonary embolism (PE) prior to discharge. The investigators will perform multivariate regression analyses to identify predictors of VTE.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Sepsis
• Severe Sepsis With Septic Shock
• Shock
• Shock, Septic

• NCT number: NCT02353910
• Study type: Observational
• Source: University of Utah
• Status: Completed
• Phase: N/A
• Start date: July 2009