Clinical Trials Logo

Clinical Trial Summary

Severe infections in pediatric intensive care unit are not uncommon. Historically, the diagnosis of hereditary (primary) immune deficiency required a combination of recurrent clinical signs and biological stigmas. This paradigm is currently being questioned, and grows the hypothesis of a potential underlying genetic susceptibility in any severe infection. To date, the proportion of severe infections explained by an underlying immune deficiency is unknown. The aim of this prospective study is to assess the incidence of primary immune deficiencies in children with severe infection, regardless of their etiology.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04990908
Study type Observational
Source University Hospital, Montpellier
Contact Eric JEZIORSKI
Phone 04 67 33 57 98
Email e-jeziorski@chu-montpellier.fr
Status Recruiting
Phase
Start date September 1, 2023
Completion date September 1, 2026

See also
  Status Clinical Trial Phase
Recruiting NCT05788861 - Invasive Group A Streptococcal Infection
Recruiting NCT05602324 - Nutritional Supplement for Patients With Severe Infection N/A
Active, not recruiting NCT02846298 - Evaluation of Pharmacokinetic / Pharmacodynamic Data and Interest Individualized Therapeutic Drug Monitoring Glycopeptides and β-lactam-aminoglycoside ICU
Recruiting NCT04650607 - Phage Safety Cohort Study
Recruiting NCT02167802 - Construction and Validation of a Tool for Automatic Identification of Care Pathways at Risk of Sub-optimality in the Management of Severe Infections in Children (DIABACT IV)
Completed NCT03145428 - Evaluation of Monocyte Volume Distribution Width (MDW) for Early Detection of Sepsis
Terminated NCT05210387 - Seven Versus 14 Days of Antibiotic Therapy for Multidrug-resistant Gram-negative Bacilli Infections N/A
Recruiting NCT06260345 - CommunautAry Pediatric bacteRial Infection in Intensive CarE Unit
Recruiting NCT06161870 - Clinical Study of Individualized Vancomycin Dosing Based on Population PK Model Phase 4
Completed NCT04621539 - Validation of the Quick Sequential [Sepsis-related] Organ Failure Assessment (qSOFA) in Obstetric Patients
Recruiting NCT06185920 - PHAGEinLYON Clinic Cohort Study: a Descriptive Study of Severe Infections Treated With Phage Therapy at the HCL.
Recruiting NCT04923828 - Chinese PICU Collaborative Network on Pathogens and Drug Resistance of Severe Infections
Completed NCT03588325 - Evaluation of MDW for Early Detection of Sepsis, Clinical Validity