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Clinical Trial Summary

This study will determine the efficacy of human-cl rhFVIII in previously treated patients with severe hemophilia A during prophylactic treatment, treatment of bleeding episodes and in surgical prophylaxis.


Clinical Trial Description

n/a


Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention


Related Conditions & MeSH terms


NCT number NCT01125813
Study type Interventional
Source Octapharma
Contact
Status Completed
Phase Phase 3
Start date June 2010
Completion date January 2012

See also
  Status Clinical Trial Phase
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Completed NCT02172950 - An Open-label Safety and Efficacy Study of Recombinant FVIII in Patients With Severe Hemophilia A Phase 3
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Active, not recruiting NCT05181618 - A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants With Severe or Moderate Hemophilia A Without Factor VIII Inhibitors on Emicizumab Prophylaxis Phase 4
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Terminated NCT01405742 - Hemophilia Adult Prophylaxis Study Phase 3
Active, not recruiting NCT04431726 - A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors Phase 3
Recruiting NCT05935358 - Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular Prophylaxis Study Phase 4
Completed NCT01712438 - Human Cell Line-derived Recombinant Factor VIII (Human-cl-rhFVIII) in Previously Untreated Patients Phase 3
Recruiting NCT06142552 - Phase 3 Clinical Project of Pegylated Recombinant Human Coagulation Factor VIII-Fc Fusion Protein Phase 3
Completed NCT02954575 - Clinical Study to Investigate the PK, Efficacy, and Safety of Wilate in Patients With Severe Hemophilia A Phase 3
Completed NCT01027377 - Study of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Subjects With Severe Hemophilia A Phase 1