Thiol/Disulfide and Oxidative Stress

Severe Early Childhood Caries Clinical Trial

Official title:

Evaluation of Saliva Thiol/Disulfide Homeostasis and Oxidative Stress in Children With Severe Early Childhood Caries by a Novel Method- Part 1

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04655859
• Other study ID #: 2020/1-19M
• Status: Completed
• Start date: May 10, 2020
• Est. completion date: September 15, 2020

Study information

• Verified date: November 2020
• Source: Kahramanmaras Sutcu Imam University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The aim of this study was to evaluate the role of thiol/disulfide homeostasis and oxidative stress in the saliva of children with severe early childhood caries

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. completion date: September 15, 2020
• Est. primary completion date: June 10, 2020
• Gender: All
• Age group: 3 Years to 5 Years

Eligibility

Inclusion Criteria:

• 3-5 years

Exclusion Criteria:

• the children with systemic illness, using anti-inflammatory drug

Related Conditions & MeSH terms

• Severe Early Childhood Caries

Intervention

Diagnostic Test:
• saliva cotton swab
evaluate the role of thiol/disulfide homeostasis and oxidative stress in the saliva of children with severe early childhood caries and healthy group

Locations

Country	Name	City	State
Turkey	Asli Sogukpinar	Kahramanmaras

Sponsors (1)

Lead Sponsor	Collaborator
Kahramanmaras Sutcu Imam University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	thiol/disulfide homeostasis	Unstimulated saliva samples were taken from all children. Then, thiol/disulfide homeostasis and antioxidant levels were evaluated.	six months