Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03303131
Other study ID # MUAC 2007-2011
Secondary ID
Status Completed
Phase N/A
First received October 2, 2017
Last updated February 1, 2018
Start date September 1, 2007
Est. completion date December 31, 2011

Study information

Verified date January 2018
Source Epicentre
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Retrospective analysis of routine program data of children aged 6 to 59 months admitted to the MSF therapeutic feeding program with MUAC ≤ 118 mm in Yako and Titao districts of Burkina Faso from 2007-2011.


Description:

Comparison of patient characteristics and treatment outcomes was conducted between two groups: 1) children discharged as recovered from September 2007 to March 2009 with at least 15% of their weight at admission (Period A); and 2) children discharged as recovered from April 2009 to December 2011 with MUAC ≥ 124 mm (Period B).

A total of 50,841 children were admitted with MUAC ≤ 118 mm to the MSF therapeutic feeding program and were included in this analysis: 24,792 children in Period A (2007-2009) and 26,049 children in Period B (2009-2011).

Overall, 89% of admissions were directly into outpatient care and the majority (53%) entered with a MUAC 116-118mm; 48% of children were male and 80% of children < 2 years of age (Table 1).

Compared to children admitted in Period A, children admitted in Period B were statistically more likely to be female, younger, and of better anthropometric status (e.g. higher mean MUAC, WHZ and HAZ).

There was a greater proportion of children admitted directly to inpatient care in Period B than in Period A (10.6% vs 8.0%).


Recruitment information / eligibility

Status Completed
Enrollment 50841
Est. completion date December 31, 2011
Est. primary completion date December 31, 2011
Accepts healthy volunteers No
Gender All
Age group 6 Months to 59 Months
Eligibility Inclusion Criteria:

- 6 to 59 months old

- presence of bipedal pitting edema or MUAC = 118 mm

Exclusion Criteria:

- < 6 months old or > 59 months old

- absence of bipedal pitting edema or MUAC = 118 mm

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Discharge from community-based management
Comparison of patient characteristics and treatment outcomes between two groups

Locations

Country Name City State
n/a

Sponsors (2)

Lead Sponsor Collaborator
Epicentre Medecins Sans Frontieres, Netherlands

Outcome

Type Measure Description Time frame Safety issue
Primary MUAC based criterion Use of a discharge criterion of MUAC = 124 mm 52 months
See also
  Status Clinical Trial Phase
Completed NCT03360877 - Prevention of Nosocomial Infections (CleanKids) N/A
Completed NCT04715204 - Gastrointestinal Tolerance of Under-five Children With Severe Acute Malnutrition to ONS Compared to F-75/F-100 N/A
Not yet recruiting NCT06038071 - Family Mid-Upper Arm Circumference (MUAC) Follow-up After Recovery From Acute Malnutrition (MODAM-fMUAC) N/A
Not yet recruiting NCT06061484 - Modified Dosage for Severe Acute Malnutrition N/A
Completed NCT03666572 - Pilot of a Prebiotic and Probiotic Trial in Young Infants With Severe Acute Malnutrition Phase 2
Completed NCT05015257 - Effectiveness of Four Transition Dietary Regimens in the Hospital Management of Children With Kwashiorkor. N/A
Completed NCT05020847 - Effectiveness of Alternative Diets During the Stabilization Phase on Children With Complicated SAM N/A
Recruiting NCT06123390 - Evaluating RISQ System Implementation in Acutely Malnourished Children in Chad (CRIMSON) N/A
Completed NCT03370003 - Non-routine Use of Antibiotics (Amoxi-light)
Recruiting NCT06002438 - Eggs for Gut Health N/A
Terminated NCT05473234 - Azithromycin for Severe Acute Malnutrition in CMAM, Nigeria Phase 3
Completed NCT01613547 - The Effect of Routine Antibiotic Use in the Outpatient Treatment of Severely Malnourished Children Without Complications N/A
Completed NCT01331044 - Ready to Use Therapeutic Food (RUTF) in Severe Malnourished Children N/A
Completed NCT03094247 - Feeding Malnourished Children Different Types of Fatty Acids to Promote Neurocognitive Development N/A
Recruiting NCT04240990 - Development of a Diagnostic Prediction Score for Tuberculosis in Hospitalized Children With Severe Acute Malnutrition N/A
Completed NCT01958905 - Efficacy and Bio-availability of Artemether-Lumefantrine in Severely Malnourished Children N/A
Completed NCT05737472 - High-protein Quantity and Quality RUTF in Improving Linear Growth Among Children With Severe Wasting N/A
Completed NCT03716115 - Therapeutic Approaches to Malnutrition Enteropathy Phase 2
Completed NCT01593969 - A Trial of n-3 PUFA-Enriched Ready to Use Therapeutic Food for Childhood Severe Malnutrition Phase 2
Completed NCT05891457 - Changes in Nerve Electro Physiologic Properties in Children Before and After Correction of Malnutrition N/A