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NCT ID: NCT05271578 Recruiting - Vascular Reactivity Clinical Trials

MRI and Biological Markers of Acute E-Cigarette Exposure in Smokers and Vapers

AeCE
Start date: June 7, 2022
Phase: N/A
Study type: Interventional

To examine vascular reactivity and inflammatory biomarkers via quantitative magnetic resonance imaging (MRI) and blood serum, respectively, in a crossover study where active vapers (electronic cigarette users) and smokers will undergo three separate acute exposure-episodes of electronic cigarette +/- nicotine and tobacco-cig. The MRI exams and blood draws will be performed pre- and post-exposure. The results will be compared against baseline values derived from a group of non-smokers/non-vapers, who will also undergo a blood draw and MRI.