Serial Endocan Measurements Clinical Trial
Official title:
Endocan; Can be a New Biomarker in Ventilator-associated Pneumonia?
In this study; in patients undergoing mechanical ventilation, making the day series Endocan measurements during the first 5 day to look at whether there is a relationship between the levels of VAP with Endocan. This relationship, if any, aimed to investigate whether correlated with clinical and laboratory findings [presence of fever, pathological lung X-ray, the number of white blood cells (WBC), procalcitonin (PCT), C-reactive protein (CRP)] .
| Status | Recruiting |
| Enrollment | 60 |
| Est. completion date | March 2017 |
| Est. primary completion date | February 2017 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - over 18 age - Patients whether intubated and connected to a mechanical ventilator Exclusion Criteria: - patients intubated due to lung problems such as COPD, asthma, pulmonary embolism , etc. - Patients with brain tumors - patients with acute and chronic renal failure - Patients with hypertension - Patients with previously diagnosed infection - Patients with extubated - patients using antibiotics or corticosteroids before bronchoalveolar lavage fluid samples taken |
Observational Model: Cohort, Time Perspective: Prospective
| Country | Name | City | State |
|---|---|---|---|
| Turkey | Erzincan University | Erzincan |
| Lead Sponsor | Collaborator |
|---|---|
| Erzincan University |
Turkey,
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* Note: There are 11 references in all — Click here to view all references
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | relationship between the level of Endocan and development of VAP | 9 month | No | |
| Secondary | correlation with the level of Endocan and clinical and laboratory findings | 9 month | No |