Mottling Score and Central Venous Oxygen Saturation in Septic Shock Patients

Septic Shock Clinical Trial

Official title:

Mottling Score and Central Venous Oxygen Saturation in Septic Shock Patients

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05681052
• Other study ID #: University of Erzincan
• Status: Recruiting
• Start date: October 1, 2022
• Est. completion date: January 21, 2023

Study information

• Verified date: January 2023
• Source: Erzincan University
• Contact: NURCAN KUTLUER KARACA, Asistant Profesor
• Phone: +905386961814
• Email: nurcankutluer[@]yahoo.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Mottling score and central venous oxygen saturation are described as a clinical evaluation of tissue perfusion. This study describes mottling incidence and mottling score in septic shock patients according to central venous oxygen saturation.

Description:

This study prospectively analyzed the data of patients admitted to our ICU between October 2022 to December 2022. All septic patients in whom the ScvO2 was measured and mottling scores were evaluated were included. This study enrolled patients aged ≥ 18 years in septic shock. Those excluded have peripheral arterial disease, black skin, cutaneous infection of the lower limbs, pregnancy, and relative refusal. The characteristics of patients were recorded at admission (H0), including demographics (age, sex, body mass index (BMI), admission the Acute Physiology and Chronic Health Evaluation (APACHE II) score, Glasgow Coma Scale (GCS) and sequential organ failure assessment (SOFA) score. Variables such as plasma lactate level, daily urine output, plasma creatinine level, the ratio of arterial oxygen pressure related to inspired oxygen fraction (PaO2/FiO2), hemoglobin level, heart rate, mean arterial pressure, pulsatile saturation in oxygen (SpO2) and body temperature were recorded at H0 and 6 hours after initial resuscitation (H6).

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 62
• Est. completion date: January 21, 2023
• Est. primary completion date: January 21, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• patients aged = 18 years in septic shock.

Exclusion Criteria:

• patients having the peripheral arterial disease

• black skin,

• cutaneous infection of the lower limbs

• pregnancy

• relative refusal

Related Conditions & MeSH terms

• Microcirculation
• Septic Shock
• Shock
• Shock, Septic

Locations

Country	Name	City	State
Turkey	Nurcan Kutluer Karaca	Erzi?ncan

Sponsors (1)

Lead Sponsor	Collaborator
Erzincan University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Difference in mottling incidence according to ScvO2 level during a septic shock.		at 0th hour, admission; at 6th hour after initial treatment
Primary	Difference in mottling score according to ScvO2 level during a septic shock.	0 score is minimum level, meaning no mottling, meaning better outcome 5 score is maximum level, meaning more mottling, meaning worse outcome	at 0th hour, admission; at 6th hour after initial treatment