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Timing of Preload Responsiveness in Sepsis — TIPRES  

Septic Shock Clinical Trial

Official title:
Timing of Preload Responsiveness in Sepsis and Septic Shock

Clinical Trial Summary

During acute circulatory failure, volume expansion does not always lead to a significant increase in cardiac output (fluid responsiveness). After initial resuscitation by rapid fluid administration, cardiac preload is no longer extremely low and only half of the patients respond to further volume expansion with the expected increase in cardiac output (fluid unresponsiveness). However, the time delay or the volume of fluid needed to be administered from the state of fluid responsiveness to fluid unresponsiveness is still not determined. Objective To determine, in critically ill patients with acute circulatory failure, 1. : the time and/or the volume of fluid needed from the state of fluid responsiveness to fluid unresponsiveness during septic shock. 2. : determine the factors that influence this time and volume.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05627817
Study type Observational
Source Bicetre Hospital
Contact Rui SHI, M.D., Ph.D.
Phone +33642170297
Email shiruidingding@hotmail.com
Status Recruiting
Phase
Start date February 20, 2019
Completion date December 2023
View Details
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