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Simplified Assessment of Left Ventricular Systolic Function in Septic Shock Patients — MAPSE  

Septic Shock Clinical Trial

Official title:
Simplified Assessment of Left Ventricular Systolic Function in Septic Shock Patients

Clinical Trial Summary

The assessment of left ventricular systolic function is based on the measurement of left ventricular ejection function (LVEF) by the Simpson biplane method. More recently, left ventricular global longitudinal strain (GLS) has been developed to detect abnormalities of cardiac contractility in patients with preserved myocardial contractility. However, both tools are not always easy to collect in practice. This is why other ultrasound parameters have been proposed in the literature as a substitute for LVEF and GLS such as the Doppler tissue imaging (DTI)-derived mitral annular systolic peak S-wave velocity (S'), the mitral annular plane systolic excursion (MAPSE) and the longitudinal wall fractional shortening index (LWFS). The purpose of this project is to propose an algorithm using simple parameters (S' wave, lateral MAPSE, septal MAPSE, mean MAPSE and LWFS) to predict LVEF and GLS in order to diagnose patients with impaired systolic function and preserved ejection.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04963686
Study type Observational
Source Centre Hospitalier Universitaire, Amiens
Contact Michel Slama, Pr
Phone 0322089809
Email slama.michel@chu-amiens.fr
Status Recruiting
Phase
Start date August 1, 2021
Completion date November 2023
View Details
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