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Correlation of VEGF-A and Fluid Balance in Septic Shock — VEGFluid  

Septic Shock Clinical Trial

Official title:
Correlation of VEGF-A and Fluid Balance in Septic Shock

Clinical Trial Summary

VEGF is a key molecule in the control of vascular permeability via interactions with the VEGF-receptor on the endothelial cell. Several authors reported plasma VEGF levels are elevated in sepsis shock and associated with increased mortality (1,2). In septic shock, the main elements of treatment are intravenous fluids, appropriate antibiotics and vasopressors. Some authors observed positive fluid balance is associated with increased mortality rates in patients (3,4). To the best of our knowledge, no studies have shown a correlation between VEGF levels and the fluid balance. The aim of our study was to determine the role of VEGF in capillary leakage and the positive fluid balance in septic shock.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04474431
Study type Interventional
Source University Hospital, Rouen
Contact Nell Marty
Phone 02 32 88 82 65
Email nell.marty@chu-rouen.fr
Status Recruiting
Phase N/A
Start date December 24, 2019
Completion date January 24, 2022
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