Low-chlorine Vs High-chlorine Crystalloids in Septic Shock Adults

Status Not yet recruiting

Clinical Trial Summary

Fluid resuscitation is an important treatment in septic shock patients, however whether crystalloid composition affects septic shock patients outcomes remains unclear. According to previous studies, low-chlorine crystalloids could significantly reduce the incidence of kidney injury and 30-day mortality compared with high-chlorine crystalloids in critically ill adults. Therefore, we hypothesized that the use of low-chlorine crystalloids would result in a lower incidence of major adverse kidney events within 30 days (MAKE 30: overall incidence of death, new renal-replacement therapy, and persistent renal dysfunction) than high-chlorine crystalloids in septic shock adults.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04365010
Study type	Interventional
Source	Southeast University, China
Contact	Haibo Qiu, MD, PhD
Phone	0086-13951965301
Email	haiboq2000@163.com
Status	Not yet recruiting
Phase	Phase 4
Start date	May 2020
Completion date	December 2021

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See also
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