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Improvement of Cerebrovascular Autoregulation in Patients With Septic Shock Due to Cytokine Elimination — SepsAR3  

Septic Shock Clinical Trial

Official title:
Verbesserung Einer gestörten zerebrovaskulären Autoregulation Bei Patienten im Septischen Schock Durch Extrakorporale Reduktion Von Entzündungsmediatoren

Clinical Trial Summary

The trial investigates the effect of cytokine elimination in patients with septic schock and acute renal failure with need for renal replacement therapy on the integrity of cerebrovascular autoregulation. Patients with inclusion criteria were randomly assign in either use of CytoSorb filter integrated in renal replacement therapy versus non additional filter an renal replacement therapy alone. Cerebrovascular autoregulation will be measured with transcranial Doppler ultrasound and correlation with arterial blood pressure.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04259567
Study type Interventional
Source Johannes Gutenberg University Mainz
Contact
Status Recruiting
Phase N/A
Start date June 8, 2020
Completion date July 31, 2022
View Details
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