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SQUEEZE Trial: A Trial to Determine Whether Septic Shock Reversal is Quicker in Pediatric Patients Randomized to an Early Goal Directed Fluid Sparing Strategy vs. Usual Care — SQUEEZE  

Septic Shock Clinical Trial

Official title:
SQUEEZE Trial: A Trial to Determine Whether Septic Shock Reversal is Quicker in Pediatric Patients Randomized to an Early Goal Directed Fluid Sparing Strategy vs. Usual Care

Clinical Trial Summary

The purpose of the SQUEEZE Trial is to determine which fluid resuscitation strategy results in the best outcomes for children treated for suspected or confirmed septic shock. In this study, eligible children will be randomized to either the 'Usual Care Arm' or the 'Fluid Sparing Arm'. Children will receive treatment according to current ACCM Septic Shock Resuscitation Guidelines, with the assigned resuscitation strategy used to guide administration of further fluid boluses as well as the timing of initiation and escalation of vasoactive medications to achieve ACCM recommended hemodynamic targets.

Clinical Trial Description

Please see published pilot trial protocol for more information about the SQUEEZE Trial and rationale for this study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03080038
Study type Interventional
Source McMaster University
Contact
Status Completed
Phase N/A
Start date March 6, 2017
Completion date December 31, 2021
View Details
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