Septic Shock Clinical Trial
Official title:
Effect of EGDT on Hepatic Perfusion in Patients With Septic Shock
To observe the effect of early goal directed therapy (EGDT) on hepatic perfusion in patients
with septic shock.
Hypothesis: Hepatic perfusion did not improved after EGDT in patients with septic shock.
Objective To observe the effect of early goal directed therapy (EGDT) on hepatic perfusion
in patients with septic shock.
Methods A prospective observational study was carried out. The eligible patients were
treated with the standard procedure of EGDT. The hemodynamic data were recorded. Oxygen
metabolism and hepatic function were monitored. Indocyanine clearance test was applied to
detect the hepatic perfusion. Hemodynamics, hepatic perfusion, oxygen metabolism and hepatic
function were compared before treatment, after EGDT and 24 hours after EGDT.
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Observational Model: Cohort, Time Perspective: Prospective
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