International Multicentre Prevalence Study on Sepsis

Septic Shock Clinical Trial

— IMPRESS  

Official title:

Surviving Sepsis Campaign. International Multicentre Prevalence Study on Sepsis.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01943747
• Other study ID #: IMPRESS
• Status: Completed
• Phase: N/A
• First received: September 12, 2013
• Last updated: August 19, 2014
• Start date: November 2013
• Est. completion date: January 2014

Study information

• Verified date: August 2014
• Source: European Society of Intensive Care Medicine
• Contact: n/a
• Is FDA regulated: No
• Health authority: Belgium: European Society of Intensive Care Medicine
• Study type: Observational

Clinical Trial Summary

To mark 10 years of the Surviving Sepsis Campaign (SSC), and timed to coincide with World Sepsis Day, on September 13, 2013, the SSC, ESICM and SCCM will be conducting an international point prevalence study of severe sepsis and septic shock. The goal of this project is to determine the world wide burden of severe sepsis and define current practices of sepsis care internationally. The study is a simple data collection exercise for patients presenting with either severe sepsis or septic shock on World Sepsis Day.

Description:

De--‐identified patient--‐level data will be collected on patients presenting to a participating intensive care unit or emergency department with severe sepsis or septic shock over a 24 hour period from 00:00 to 24:00 November 07, 2013. De--‐identified data that is already collected as part of routine clinical care will be collected for this study. Data to be collected includes hospital and ICU characteristics, patient characteristics, severity of illness, and adherence to SSC bundle elements and mortality. It will take between 30--‐60 minutes to collect and enter data for each patient admitted with severe sepsis or septic shock over the 24 hours study period.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1000
• Est. completion date: January 2014
• Est. primary completion date: November 2013
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

To be eligible patients must have all of the following:

• Must be admitted or transferred to either the ED or an Intensive Care Unit.

• Have a high clinical suspicion of an infection

• Have sepsis as defined by an infection together with two or more SIRS criteria

• Evidence of acute organ dysfunction and/or Shock.

Exclusion Criteria:

• Patients less than 18 years of age

• Patients in whom the sepsis has been present from before the beginning of the study period

• Any patients previously included in the study during the same study period

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Sepsis
• Septic Shock
• Severe Sepsis
• Shock, Septic
• Toxemia

Locations

Country	Name	City	State
Belgium	All centres willing to contribute are welcome.	Brussels

Sponsors (2)

Lead Sponsor	Collaborator
European Society of Intensive Care Medicine	Society of Critical Care Medicine (SCCM)

Country where clinical trial is conducted

Belgium, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Length of Stay in the Hospital		one week	No
Primary	28-Day Mortality		one week	No
Secondary	Organ Failure		one week	No

External Links

•   Link