Septic Shock Clinical Trial
Official title:
Near Infrared Spectroscopy (NIRS) to Measure Tissue Oxygen Saturation (St02)
The overall hypotheses of this project is that Near Infrared Spectroscopy (NIRS) can be used to identify morbidity, mortality, and resource utilization in patients with sepsis and septic shock.
Near-infrared spectroscopy (NIRS) noninvasively measures peripheral tissue oxygen saturation
(StO2), offering promise as a guide in the early treatment of severe sepsis; however, the
role and utility of this technology is still evolving.
There are three main NIRS measurements reported in the literature: continuous StO2
measurement (StO2 initial), StO2 occlusion slope (StO2 downslope) in response to VOT testing
and StO2 recovery slope (StO2 upslope) in response to vasoocclusive testing. The purpose of
this study is to assesses the association of each of these parameters with severity of
illness, organ dysfunction and death.
This study will utilize the Hutchinson InSpectra StO2 tissue oxygenation monitor, which is
FDA approved for use in monitoring patients during circulatory or perfusion examinations of
skeletal muscle, or when there is a suspicion of compromised circulation.
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