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Autonomic Nervous System Alteration Induce by Sepsis: Assessment and Prognosis Impact — SNA&Sepsis  

Septic Shock Clinical Trial

Official title:
Autonomic Nervous System Alteration Induce by Sepsis:Assessment and Prognosis Impact

Clinical Trial Summary

Severe sepsis and septic shock are causes of admission in intensive care units.Modification of natriuretic peptid including NT-proBNP and cardiac autonomic nervous system alteration are reported in sepsis shock and severe sepsis and seems to link to patient prognosis admitted to intensive care units.

Clinical Trial Description

Our principal aim is to characterize modulation of cardiac sympathic nervous system in sepsis through the study of sinusal change and myocardiac fixing of MIBG.

The second aim is 1)to assess links between alteration of cardiac sympathic nervous system and NT-PRoBNP variations in sepsis and 2)To know prognostic impact in sympathic nervous system compare to NTproBNP. ;

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00835913
Study type Observational
Source University Hospital, Grenoble
Contact
Status Completed
Phase Phase 4
Start date October 2008
Completion date September 2011
View Details
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