Clinical Trials Logo

Clinical Trial Summary

Detect short term results of pediatric septic hip arthritis and its risk factors


Clinical Trial Description

Septic arthritis of the hip is a true orthopedic emergency(1). In developed countries, the incidence of acute bacterial septic arthritis is estimated to be 4 to 10 per 100,000 children (2).It is caused by many microorganisms. Staph aureus is most common in children over 2 years of age . Staph aureus is gram-positive cocci in clusters and most common in nosocomial infections of neonates(3-4).Group B streptococcus is most common in neonates with community-acquired infection and exposed during transvaginal delivery(5).Neisseria gonorrhoeae is gram-negative diplococci and most common in adolescents.when the causative Organism is Neisseria gonorrhoeae ,patients usually have a preceding migratory polyarthralgia,multiple joint involvement and small red papules(6-7).Group A beta-hemolytic streptococcus is most common organism following varicella infection.HACEK organisms (Haeophilus,Actinobacillus,Cardiobacterium,Eikenella,and Kingella fastidious) are less common causative organisms(8-9).Early diagnosis and accurate treatment is key in avoiding complications such as joint destruction,joint dislocation , ankylosis, growth arrest or spread of infection leading to osteomyelitis , pelvic abscess or nerve lesions.. Treatment is started without delay after synovial fluid and blood samples have been obtained. The classical presentation of septic hip arthritis in children is a combination of a painful hip joint with limited range of motion, fever, malaise and inability to bear weight on the affected limb. Misdiagnosis or inappropriate treatment of acute septic arthritis of the hip in children can result in devastating damage of the joint and possible lifelong disability. Open arthrotomy , drainage and thorough irrigation of the joint is considered the standard treatment for septic arthritis of the hip.Empiric antibiotic treatment primarily targets S. aureus and takes into account its resistance to antibiotics(10-11). So,we want to detect short term results of pediatric septic hip arthritis at Assiut University Hospitals ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05780697
Study type Interventional
Source Assiut University
Contact Beshoy Elkes Abram, Resident Dr
Phone 01284144493
Email Beshoelghalban_2010@yahoo.com
Status Not yet recruiting
Phase N/A
Start date March 2023
Completion date March 2025

See also
  Status Clinical Trial Phase
Not yet recruiting NCT06003374 - Extended Hip Ultrasound as Anew Protocol for Septic Hip in Children
Active, not recruiting NCT04563325 - Oral-only Antibiotics for Bone and Joint Infections in Children Phase 4
Completed NCT05341908 - Prevalence of Pathogens in Synovial Fluid Obtained From Emergency Department Patients
Completed NCT03846804 - Next-Generation Sequencing for Pathogen Detection and Quantification in Children With Musculoskeletal Infections N/A
Completed NCT00503438 - Ankle Joint Replacement Outcomes Study
Recruiting NCT04952220 - Exploratory Study of Ultrasound Signs of Native Septic Arthritis of the Knee
Active, not recruiting NCT02565160 - Analysis of Human Knee Joint Fluid Using Metabonomic, Genomic and Tribology Techniques
Recruiting NCT05971745 - Accuracy of Pediatric Emergency Medicine Providers in Diagnosing Hip Effusions Using Point of Care Ultrasound
Completed NCT05593874 - Predictive Value of Nu.Q™ Biomarkers to Help Guiding the Management of Osteoarticular Infections
Recruiting NCT02530229 - Arthrocentesis Study N/A
Not yet recruiting NCT05521880 - Anchoring Sequential Intermittent Long Acting Antimicrobials With Medication for Opioid Use Disorder (MOUD) for Invasive Infections Related to Opioid Use Phase 4
Completed NCT03802552 - Cefadroxil and Cephalexin Drug Levels and Dosing in Pediatric Musculoskeletal Infections Phase 1
Recruiting NCT03704766 - Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis N/A
Not yet recruiting NCT05886166 - Clinical Utility of Exoskeleton Robot Training in Patients With Septic Arthritis After a Thermal Injury: A Case Report N/A
Recruiting NCT04538053 - BonE and Joint Infections - Simplifying Treatment in Children Trial Phase 4
Recruiting NCT04141787 - Ceftriaxone as Home IV for Staph Infections Phase 4
Completed NCT06241365 - The Predictive Role of C-reactive Protein to Albumin Ratio (CAR) in the Treatment of Septic Arthritis in Young Chlidren
Completed NCT03426761 - Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections Phase 4
Completed NCT02018952 - Ultrasonography Assessment of Septic Arthritis on Native Joint N/A
Recruiting NCT04284423 - Study of Synovial Lactate Level as Marker of Septic Arthritis