Septic Abortion Clinical Trial
Official title:
Prolonged Treatment for Infected Abortion After Hospital Discharge.
Patients with infected abortion will be treated with dilatation and curettage, intravenous antibiotics. The purpose of this study is to verify if it is necessary to keep the use of oral antibiotics after hospital discharge.
The use of 7-10 days of treatment for infected/septic abortion is not based on clinical
trials. A recent evidence showed that endometritis post cesarean section needs no treatment
after hospital discharge. The objective of this study is to verify if this finding also
applies to infected abortions.
After in hospital treatment, the patients will be randomized to the traditional treatment
(metronidazole and doxycycline) or to placebo until 10 days of treatment is completed.
Active follow-up will be done every 2 days, and the patient will be reevaluated at the end
of treatment.
Cure will be defined as the absence of fever, pain and bleeding. Failure of treatment will
be considered as the need for hospitalization or additional antibiotics.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT02309346 -
Clindamycin Once a Day in Septic Abortion
|
Phase 4 |