Sepsis Newborn Clinical Trial
Official title:
The Effect of Melatonin as an Adjuvant Therapy for Preterm Neonates With Sepsis (Review of Malondialdehyde, Interleukin-6, Interleukin-8, Absolute Neutrophil Counts, and Sepsis Score)
The goal of this clinical trial is to assess the effect of melatonin on MDA serum, IL-6, IL-8 levels, ANC, and sepsis score in preterm neonates with sepsis. The main question aim to answer : • Does melatonin affect MDA serum, IL-6, IL-8 levels, ANC, and sepsis score in preterm neonates with sepsis? The participants in the treatment group will receive a single dose of oral melatonin 20 mg, meanwhile those the control group will receive placebo. The researchers will compare MDA serum, IL-6, IL-8 levels, ANC, and sepsis score before and after receiving melatonin, whether there are decreases of MDA serum, IL-6, IL-8 levels, ANC and increase of sepsis score
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT03111329 -
Does Routine Assessment of Gastric Residuals in Preterm Neonates Influence Time Taken to Reach Full Enteral Feeding?
|
N/A | |
| Completed |
NCT03136172 -
Monitoring of Systemic or Organ Perfusion for Preterm Infants
|
||
| Completed |
NCT03078335 -
Glove-based Care in the NICU to Prevent Late Onset Sepsis
|
N/A | |
| Completed |
NCT03923543 -
Is Neutrophil to Lymphocyte Ratio a Prognostic Factor of Sepsis in Newborns With Operated Congenital Heart Disease
|
||
| Recruiting |
NCT05121753 -
Infant Formula Feeding and Necrotizing Enterocolitis in Newborns
|
||
| Completed |
NCT03275090 -
The Effects of Two Different Intravenous Lipid Emulsions on the Outcomes of Preterm Infants With Sepsis
|
Phase 4 | |
| Recruiting |
NCT05604846 -
Probiotic Supplementation in Extremely Preterm Infants in Scandinavia
|
N/A | |
| Completed |
NCT03780712 -
Immune Dysfunction in Newborn Sepsis
|