Central Venous Catheter Related Bacteremia Clinical Trial
Official title:
Clinical Phase IV Comparison Trial for 2% Chlorhexidine Skin Asepsis +70% Alcohol Versus Aqueous Chlorhexidine (2%) for the Prevention of Catheter-related Bacteremia in Critical Patients: Preliminary Study
A multicentre, open-label clinical trial of two groups comparing cutaneous asepsis with chlorhexidine gluconate at 2% + isopropyl alcohol 70% in relation to the placement of central venous catheters (Study group) with standard asepsis with aqueous chlorhexidine at 2% (Group Control). The incidence of catheter related bacteremia, the incidence of colonization of the skin and the incidence of colonization of the central venous catheter will be evaluated.
A multicentre, open-label clinical trial of two groups comparing cutaneous asepsis with
chlorhexidine gluconate at 2% + isopropyl alcohol 70% in relation to the placement of central
venous catheters (Study group) with standard asepsis with aqueous chlorhexidine at 2% (Group
Control). The incidence of catheter related bacteremia, the incidence of colonization of the
skin and the incidence of colonization of the central venous catheter will be evaluated.
The patients will assigned to the treatment group depending on where and when they are
treated (site A or site B) and will continue the treatment until the end (continuous design):
the patients of Site A will receive the first treatment option and those of Site B will
receive the second treatment option during the first 6 months. After this, a rest period of 1
month will be established, during which patients will not be recruited and any of the two
cutaneous aseptic methods will be used indiscriminately, in the opinion of the responsible
nursing staff. After the resting period, the treatments will be reversed during the following
6 months.
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