Sensitivity Clinical Trial
Official title:
Effects of Desensitizing Dentifrices on the Reduction of Pain Sensitivity Caused by In-office Dental Whitening: Double Blind Controlled Clinical Study
Introduction: The pain sensitivity associated with whitening is the main problem reported by
patients during dental whitening, and the use of desensitizing dentifrices is an alternative
for the treatment of sensitivity.
Objective: To evaluate clinically the influence of desensitizing dentifrices applied through
a plastic tray, reducing the pain sensitivity and color variation caused by the technique of
in-office dental whitening, through a controlled double-blind clinical study.
Methods: A longitudinal prospective study was conducted with 48 individuals, 18 years and 30
years of age, without gender distinction, who underwent in-office dental whitening using 35%
hydrogen peroxide (Whiteness HP, FGM, Joinville , SC, Brazil) in three clinical sessions
with a one-week interval between them. The volunteers used in the night for each bleaching
session a plastic tray for 4 hours containing one of the dentifrices related to the
experimental groups: Group 1 (Control) - Sucralose (S) (Biotype - Manipulation pharmacy);
Group 2 (Active control) - Sodium fluoride (FS) with 1450ppm of fluorine (Close up triple,
Unilever); Group 3 - Arginine, calcium carbonate (ACC) and sodium monofluorophosphate with
1450 ppm fluorine (Colgate sensitive pro-relief, Colgate-Palmolive); Group 4 - 5% potassium
nitrate (NP) and sodium fluoride with 1450 ppm fluorine (Sensodyne pro-enamel,
GlaxoSmithKline). The evaluation of the sensitivity associated with the times of use of the
plastic tray in the first session (S1: sensitivity before the tray, S2: sensitivity after
the tray), in the second session (S3: sensitivity before the tray, S4: in the third session
(S5: sensitivity before the tray, S6: sensitivity after the tray) used the analog numerical
scale with scores from 0 to 10 and for the color evaluation the spectrophotometer
(Easyshade, Vident, Brea, CA, Obtaining the data that were used in the CIELab system. The
data were submitted to the multivariate analysis of variance (MANOVA) with repeated
measurements and Lambda Wilks test with a 5% probability level to differentiate the groups.
In addition, the factorial variance analysis (ANOVA) in one criterion was applied. Values of
p <0.05 were considered statistically significant.
n/a
Allocation: Randomized, Intervention Model: Factorial Assignment, Masking: Double Blind (Caregiver, Investigator), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03283072 -
Effects of Acute Intermittent Hypoxia on Sensory Function in Healthy Adults
|
N/A | |
| Completed |
NCT04757454 -
Performance Indicators of the SARC-F Questionnaire in Acute Care
|
||
| Completed |
NCT03792178 -
Evaluation of Post-operative Sensitivity of Bulk Fill Resin Composite Versus the Nano Resin Composite.
|
N/A | |
| Recruiting |
NCT02834585 -
Magnetic Resonance Imaging or Ultrasound in Soft Tissue Tumors (MUSTT)
|
N/A | |
| Not yet recruiting |
NCT06448169 -
Observational Study on the Sensitivity of Neoadjuvant Immunotherapy in Early Triple-Negative Breast Cancer
|
||
| Recruiting |
NCT02825407 -
Creation and Characterization of Two Groups of Subjects to Evaluate Sensitivity
|
N/A | |
| Terminated |
NCT05429307 -
Turkish Adaptation, Validity and Reliability of Exercise Sensitivity Questionnaire
|
||
| Completed |
NCT04477408 -
Effect of Plantar Sensory Exercises on Balance and Fall Risk in Nursing Home Elderly
|
N/A | |
| Recruiting |
NCT04505046 -
Validation of INSPiRED Innovative Smart Diagnostic Devices for the Detection of Parasites Infections.
|
||
| Not yet recruiting |
NCT04762940 -
INTENSIVE TREATMENT WITH ROBOTIC PLUS VIBRATION IN STROKE
|
N/A | |
| Completed |
NCT05474521 -
Evaluation of Illinois Agility Performance With Smartphone Applications: A Validity and Reliability Study
|
N/A | |
| Completed |
NCT03568695 -
Detection of Chlamydia Trachomatis, Neisseria Gonorrhoeae and Mycoplasma Genitalium by Real-time Multiplex Polymerase Chain Reaction (PCR) After Pooling Pharyngeal, Anorectal and Urinary Samples
|
N/A | |
| Completed |
NCT03031392 -
Sensitivity and Specificity of Peri-Implantitis-Related Parameters
|
N/A | |
| Not yet recruiting |
NCT04091776 -
CT Scan in Per-trochanteric Fractures
|
N/A | |
| Not yet recruiting |
NCT05185544 -
Combining Genomics and Imageomics to Predict the Sensitivity of Neoadjuvant Pemetrexed and Cisplatin Chemotherapy in Patients With Lung Adenocarcinoma
|
||
| Recruiting |
NCT03358992 -
Clinical Evaluation for Sarcoma Originated From Bone
|
||
| Recruiting |
NCT05811559 -
Investigation of Sensory Processing Patterns of Elderly Individuals Who Have Had Hip Fracture Surgery
|
||
| Recruiting |
NCT04700748 -
Diffusion-weighted MRI to Predict Treatment Response in Stereotactic Radiotherapy of Central Nervous System (CNS) Metastases
|
N/A | |
| Completed |
NCT05024669 -
Efficacy of Desensitizers in Reducing Post-operative Sensitivity Following Composite Restorations
|
N/A |