Quantitative Sensory Testing in Subjects With Sensitive Skin or Not

Sensitive Skin Clinical Trial

— SENSISKIN  

Official title:

Quantitative Sensory Testing in Subjects With Sensitive Skin or Not

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03081403
• Other study ID #: SENSISKIN 29CRB16.0100
• Status: Completed
• Phase: N/A
• First received: March 10, 2017
• Last updated: October 18, 2017
• Start date: April 14, 2017
• Est. completion date: October 17, 2017

Study information

• Verified date: October 2017
• Source: University Hospital, Brest
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin.

The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers.

The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Description:

Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin. A sensitive skin is characterized by the occurrence of tingling sensations, tightness, heat, burning, itching or pain triggered by non pathogenic factors such as wind, heat, cold, water , cosmetics, toiletries, stress...

The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers.

The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 42
• Est. completion date: October 17, 2017
• Est. primary completion date: September 22, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 60 Years

Eligibility

Inclusion Criteria:

• Age: between 20 and 60 years

• Cooperating patient

• Informed and written consent of the subject

• Affiliated to the social security

• For subjects with sensitive skin:

subjects with a score greater than 50 on the scale sensitive scale

• To control subjects: subjects with result of less than 20 sensitive to the scale scale

Exclusion Criteria:

• Adults subject with legal protection

• Subject in a social institution.

• Subject with major cognitive or psychiatric disorders

• Subject with pathological use of alcohol or consumption of another drug.

• Subject with skin involvement of the back of the dominant hand or malformation.

• Known sensitive neuropathy

• Pregnant woman

• Subject receiving medical treatment which may interfere with the results.

• Subject with treatment in the back of the dominant hand.

Related Conditions & MeSH terms

• Hypersensitivity
• Sensitive Skin

Intervention

Device:
• Quantitative Sensory Testing
Study of detection thresholds of vibration, cold and pain related to the heat in the dominant hand of the subjects through the QST.

Locations

Country	Name	City	State
France	CHRU de Brest	Brest

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Brest

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Cutaneous perception threshold	The cutaneous perception threshold of pain to heat.	6 months
Secondary	The cutaneous perception threshold of vibration	The cutaneous perception threshold of pain to harm.	6 months
Secondary	The cutaneous perception threshold of cold	The cutaneous perception threshold of cold	6 months