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Seizures, Generalized clinical trials

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NCT ID: NCT05339126 Recruiting - Epilepsy Clinical Trials

RNS System LGS Feasibility Study

Start date: October 4, 2022
Phase: Phase 2
Study type: Interventional

To generate preliminary safety and effectiveness data for brain-responsive neurostimulation of thalamocortical networks as an adjunctive therapy in reducing the frequency of generalized seizures in individuals 12 years of age or older with Lennox Gastaut Syndrome (LGS) who are refractory to antiseizure medications. The intent is to determine the feasibility and the optimal design of a subsequent pivotal study in order to expand the indication for use for the RNS System as a treatment for patients with medically intractable LGS.

NCT ID: NCT03934268 Recruiting - Seizures Clinical Trials

A Cohort Study on the Prognosis of Neonatal KCNQ2 Gene-associated Epileptic Encephalopathy

Start date: January 1, 2017
Phase:
Study type: Observational

The researchers hope to explore the etiological distribution and influencing factors of KCNQ2-related neonatal convulsions or refractory epileptic encephalopathy, and to improve the level of assessment, identification, intervention and shunt of KCNQ2-related convulsions. To formulate countermeasures and measures for prevention, management and health education.