The Differences Between Gonadal and Extra-gonadal Malignant Teratomas
SEER Database Clinical Trial
Official title: The Differences Between Gonadal and Extra-gonadal Malignant Teratomas in Both Genders and the Effects of Chemotherapy
Clinical Trial Summary
A tumor comprising of different types of tissues (such as hair, muscle, bone, etc.) is known
as a teratoma. It is a type of germ cell (cells that make sperm or eggs) tumor. When these
germ cells have rapid cancerous growth, then such a teratoma is called a malignant teratoma.
We have studied the differences between gonadal and extra-gonadal malignant teratomas and the
effects of chemotherapy in both genders.
Methods: The samples of 3799 male and 1832 female patients with malignant teratoma samples,
between the ages of 1 and 85+ years, were selected from the years 1973 to 2014. Trends in
incidence, estimated prevalence, incidence rates, and frequency were calculated in gonadal
and extra-gonadal tumors with age adjustment. The fiveyear observed, expected, and relative
survival rates were analyzed to study the prognosis.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
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Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.