Intervention Study to Investigate Supplemental Oxygen in COPD

Status Recruiting

Clinical Trial Summary

The purpose of this trial is to study the effects on exercise capacity, physical activity, inflammatory markers and quality of life of supplemental ambulatory oxygen, to be used during physical activity, in patients with COPD who are normoxic at rest but hypoxemic during a six-min walk test. Our hypothesis is that if patients are able to use supplemental oxygen they will be more physically active and thereby improve health related quality of life.

Clinical Trial Description

Study design The study will employ a parallel design for 6 months including 144 patients (72 patients/group). Patients will be randomized to intervention or control group. The intervention comprises supplemental oxygen to be used during physical activity for 6 months. The control group will receive the same physical activity instructions as the intervention group during the 6 months, but they will not be able to use supplemental oxygen during physical activity. The study will be a prospective, randomized, single-blind multi-centre intervention study with an intention to treat design (last value carry over). Inclusion will continue until 144 patients have fulfilled the 6 months. Patients will be tested at baseline and after 6 months. There will also be a follow-up after 12 months comprising questionnaires. The study will include centers in Sweden Norway, Finland, and Estonia. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01783808
Study type	Interventional
Source	Uppsala University
Contact	Margareta I Emtner, PhD
Phone	+46184714761
Email	margareta.emtner@neuro.uu.se
Status	Recruiting
Phase	N/A
Start date	November 2012
Completion date	December 2023

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