Effects of Training in Healthy Sedentary Subjects

Sedentary Subjects Clinical Trial

Official title:

Cellular Effects of Training in Healthy Sedentary Subjects

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01183039
• Other study ID #: 2008-A00209-46
• Status: Completed
• Phase: N/A
• First received: August 16, 2010
• Last updated: September 3, 2012
• Start date: May 2008
• Est. completion date: December 2010

Study information

• Verified date: September 2012
• Source: 5 Santé
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to understand underlying mechanisms of improved exercise tolerance in Healthy Sedentary Subjects after training program.

Description:

Training protocol used is based on recommendations. A minimum of 20 sessions in 4-6 weeks were proposed. The exercise intensity of exercise corresponds to target heart rate at ventilatory threshold measured during incremental exercise test. Training at this intensity allowed us to individualize effort for each patient.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: December 2010
• Est. primary completion date: December 2010
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 50 Years to 75 Years

Eligibility

Inclusion Criteria:

• healthy Sedentary Subjects

Exclusion Criteria:

• neuromuscular disease

• chronic heart failure

• diabetes

• renal diseases

• liver diseases

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label

Related Conditions & MeSH terms

• Sedentary Subjects

Intervention

Other:
• Training
20 sessions of training

Locations

Country	Name	City	State
France	Clinique du souffle La valonie	Lodeve
France	hopital Arnaud de Vilneuve	Montpellier
France	Clinique du souffle La solane	Osseja

Sponsors (3)

Lead Sponsor	Collaborator
5 Santé	Centre Hospitalier Régional Universitaire Montpellier, Institut National de la Santé Et de la Recherche Médicale, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Effects of training program on mitochondrial function and oxidative stress		6 to 8 weeks	No
Secondary	Relationship between mitochondrial function, oxidative stress and exercise tolerance in COPD patients		6 to 8 weeks	No