Polyphenols and Endothelial Function

Sedentary Subjects Clinical Trial

Official title:

Polyphenols Rich Fruit Juice Effects on Endothelial Function and Exercise Capacity

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT00619749
• Other study ID #: 4125
• Status: Terminated
• Phase: Phase 3
• First received: February 7, 2008
• Last updated: July 7, 2016
• Start date: March 2008
• Est. completion date: March 2012

Study information

• Verified date: July 2016
• Source: University Hospital, Strasbourg, France
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)
• Study type: Interventional

Clinical Trial Summary

To determine whether fruit juice rich in polyphenols might increase exercise capacity and memory in healthy sedentary subjects.Both parameters might be improved because of the anti-oxidant effects of polyphenols.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 50
• Est. completion date: March 2012
• Est. primary completion date: February 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 30 Years to 60 Years

Eligibility

Inclusion Criteria:

• sedentary

Exclusion Criteria:

• diabetes

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention

Related Conditions & MeSH terms

• Sedentary Subjects

Intervention

Dietary Supplement:
• juice rich in polyphenols
juice during 2 weeks
• juice poor in polyphenols
juice during 2 weeks

Locations

Country	Name	City	State
France	Service de Physiologie et Explorations Fonctionnelles Hôpitaux Universitaires	Strasbourg

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Strasbourg, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Flow-mediated dilatation		2 years	No
Secondary	Exercise, capacity memory		2 years	No