Sedentary Lifestyle Clinical Trial
Official title:
Exercise, Cognitive Function and Neuroplasticity in Healthy Adults
Verified date | November 2021 |
Source | University of Miami |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The overall goal of the proposed study is to compare the effects of 4 weeks of moderate or high intensity aerobic exercise on neuroplasticity, cognitive performance and gait and postural control in sedentary healthy adults.
Status | Completed |
Enrollment | 19 |
Est. completion date | October 31, 2021 |
Est. primary completion date | January 21, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 70 Years |
Eligibility | Inclusion Criteria: - Adult males and females aged 18-70 years old - Primary language is English - Sedentary (defined as not engaging in purposeful physical activity more than 2 times over the last two months) - Exercise clearance Exclusion Criteria: - Presence of cognitive, neurologic or orthopedic conditions that could affect performance of the testing and training procedures - History of migraines. - History of fainting spells of unknown or undetermined etiology that might constitute seizures - History of seizures, diagnosis of epilepsy, history of abnormal (epileptiform) EEG or family history of treatment resistant epilepsy - Any current history of a psychiatric illness - Any unstable medical condition - No medication is an absolute exclusion from TMS. Medications will be reviewed by the Principal Investigator and a decision about inclusion will be made based on the following: - The subject's past medical history, drug dose, history of recent medication changes or duration of treatment, and combination with other CNS active drugs. - The published TMS guidelines review medications to be considered with TMS (Rossi, Hallett, Rossini, Pascual-Leone, & Safety of TMS Consensus Group, 2009). - Any metal in the brain, skull or elsewhere unless approved by the responsible MD - Any medical devices (i.e. Cardiac pacemaker, deep brain stimulator, medication infusion pump, cochlear implant, vagal nerve stimulator) - Intracranial lesion - Substance abuse or dependence within the past six months Subjects who, in the Investigator's opinion, might not be suitable for the study |
Country | Name | City | State |
---|---|---|---|
United States | University of Miami Miller School of Medicine | Miami | Florida |
Lead Sponsor | Collaborator |
---|---|
University of Miami |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in cortical synaptic plasticity using transcranial magnetic stimulation (TMS) from baseline to post-exercise. | Plasticity with TMS | Baseline, 4 weeks |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02385591 -
Innovative Physical Activity Interventions for Overweight Latinos
|
N/A | |
Completed |
NCT02672215 -
RCT Computer-tailored Intervention on Workplace Sitting
|
N/A | |
Completed |
NCT03305731 -
Activating Behavior for Lasting Engagement After Stroke
|
N/A | |
Recruiting |
NCT04195165 -
The Effect of Sitting and Moderate Exercise on Plasma Insulin and Glucose Responses to an Oral Glucose Tolerance Test
|
N/A | |
Completed |
NCT03119610 -
The Physiologic Effects of Intranasal Oxytocin on Sarcopenic Obesity
|
Phase 1/Phase 2 | |
Active, not recruiting |
NCT02467881 -
Physical Activity and Sedentary Behavior Change; Impact on Lifestyle
|
N/A | |
Terminated |
NCT02254902 -
Physical Activity and Education Program for Somali Women
|
N/A | |
Completed |
NCT02342301 -
Cardiometabolic Response to Sit-stand Workstations.
|
N/A | |
Completed |
NCT01975870 -
A stAPP to a Healthier Lifestyle
|
N/A | |
Completed |
NCT02024061 -
Treatment of Pediatric Obesity (TOP) - A Multidisciplinary Approach Involving Adolescents and Their Peers
|
N/A | |
Completed |
NCT02960750 -
Effectiveness of a Workplace "Sit Less and Move More" Web-based Program in Spanish Office Employees (Walk@WorkSpain)
|
N/A | |
Completed |
NCT00183014 -
Caminemos! Trial to Increase Walking Among Sedentary Older Latinos
|
N/A | |
Completed |
NCT04049162 -
Blueberry Enhances Activity and Cognition Through Increased Vascular Efficiency
|
N/A | |
Completed |
NCT03283904 -
Active Schools: Skelmersdale
|
N/A | |
Completed |
NCT03694951 -
The Effect of Experimentally Decreasing Sedentary Behaviour on Subjective Well-being
|
N/A | |
Enrolling by invitation |
NCT04019119 -
Digital Intervention for the Modification of Lifestyles (iGame)
|
N/A | |
Completed |
NCT03109535 -
MapTrek for Sedentary Workers
|
N/A | |
Completed |
NCT03993652 -
Kids FIRST: Family-based Intervention to Reduce Snacking and Screen Time in Children
|
N/A | |
Completed |
NCT00891514 -
Trial of Aerobic Exercise Training in Stroke Survivors
|
N/A | |
Completed |
NCT03236597 -
Assessing the Effects Of Treadmill On LPA, Sitting Time, and Cardiovascular Risk
|
N/A |