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Sedation Complication clinical trials

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NCT ID: NCT06044298 Not yet recruiting - Frailty Clinical Trials

Advers Events in Patients Undergoing Gastrointestinal Procedural Sedation

Start date: January 2024
Phase:
Study type: Observational

Investigators will include in our study patients aged 60 and over who have been evaluated in the pre-anesthesia clinic for procedures such as endoscopy, colonoscopy, ERCP, PEG, EUS, and ESD, and who have received sedation by an anesthesiologist. Patients will be assessed for frailty prior to the procedure; during and after the procedure, respiratory monitoring (SpO2, capnography) will be closely observed, and they will be contacted by phone three days later. Primary goal of the study is to prospectively investigate the incidence of peri-procedural complications (desaturation, bradycardia, hypotension, etc.) in elderly patients undergoing gastrointestinal procedural sedation, and to assess its relationship with detected frailty using the FRAIL scale.Secondary goals of the study are to identify risk factors for adverse events, examine the relationship of these factors with 'ASA score - age and frailty scale', and determine their impact on the incidence of adverse events. Additionally, investigators aim to research the effects of capnography-based respiratory monitoring on adverse events.

NCT ID: NCT05708651 Not yet recruiting - Hypoxia Clinical Trials

Evaluation of Medical Device for Airway Patency During Sedation (SW01-2022)

Start date: February 2023
Phase: N/A
Study type: Interventional

The goal of this four-part preclinical [I-II] and clinical [III-IV] trial is to compare, with randomised crossover study design [I-IV], a new medical airway device with standard procedure (biteblock or no device) for upper airway patency during sedation with intravenous propofol [I-IV]. - Page 1 of 9 [DRAFT] - The two main questions it aims to answer are if this new airway device is superior to standard procedure with respect to - maintenance of spontaneous ventilation [I] and upper airway volumes [II] at moderate and deep steady-state levels of sedation in healthy volunteer study participants, and - fewer and less lasting bedside signs of respiratory depression [III-IV], and less adjuvant use of manual airway support [III-IV] during procedural sedation (PS) according to standard of care(SOC) in study patients scheduled for colonoscopy or ureteral catheterisation under PS. Owing to the crossover study design used throughout the trial, there are no comparison groups of study participants [I-II] or study patients [III-IV].

NCT ID: NCT05423821 Not yet recruiting - Clinical trials for Sedation Complication

Non-operating Room Anesthesia Experiences in Pediatric Magnetic Resonance Imaging Cases

Start date: June 14, 2022
Phase:
Study type: Observational

In recent years, out patient anesthesia applications have been increasing for diagnostic and interventional procedures for pediatric patients. In this study, we aimed to retrospectively analyze the anesthesia applications performed in pediatric MRI cases in our hospital. It is a retrospective study

NCT ID: NCT04922814 Not yet recruiting - Clinical trials for COVID-19 Acute Respiratory Distress Syndrome

Comparison for the Effect of Neuromuscular Blocking Agents Versus Sedation Alone on Severe ARDS Patients Due to COVID-19

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

Many questions about management of COVID-19 are still not answered. So, we recruit this study aiming to evaluate improvement of oxygenation in COVID-19 patients with severe ARDS, to improve morbidity and mortality of ICU covid patients, to participate in understanding of real hidden pathophysiology of COVID-19.