Comparative Analysis of Cost-effectiveness of Silver Dressing in Burns — ARGENTUM  

Second-degree Burn Clinical Trial

Official title: Comparative Analysis of Cost-effectiveness of Silver Dressing in Burns

Status Completed

Clinical Trial Summary

The evidence is insufficient to determine whether the types of dressings containing silver differ in time / proportion for complete wound healing and pain. We will analyze the cost-effectiveness of these dressings in outpatients, considering the service provided by the Brazilian National Public Health System.

Clinical Trial Description

Randomized, single-center, single-blinded, controlled clinical trial. Adult patients (age between 18 and 65 years), regardless of sex, with second degree burns treated in outpatient regimen will be randomized (1:1) into two groups: 1% silver sulfadiazine and nanocrystalline silver.

Primary outcome:

• Proportion of lesions completely epithelialized within 15 days.

Secondary outcomes:

• Time in days for complete epithelialization of the burned areas;

• Number of dressing changes;

• Level of pain associated with the application and removal of the dressings;

• Direct medical and non-medical costs;

• Need for surgery;

• Incidence of infection;

• Presence of local adverse reactions. ;

Related Conditions & MeSH terms

• Burns
• Second-degree Burn

• NCT number: NCT02108535
• Study type: Interventional
• Source: University of Sorocaba
• Status: Completed
• Phase: Phase 4
• Start date: November 2013
• Completion date: October 2014