Is Cryosurgery or Curettage More Effective at Treating Seborrheic Keratoses?

Seborrheic Keratosis Clinical Trial

Official title:

Is Cryosurgery or Curettage More Effective at Treating Seborrheic Keratoses?

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01159860
• Other study ID #: IRB Protocol No. 33895
• Status: Completed
• Phase: N/A
• Start date: July 2010
• Est. completion date: June 6, 2013

Study information

• Verified date: May 2018
• Source: Milton S. Hershey Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Seborrheic keratoses (SK's) are very common, but harmless skin lesions that commonly appear during adult life. Patients with seborrheic keratoses frequently desire treatment due to symptoms of itching and irritation or for cosmetic purposes. Seborrheic keratoses can be easily removed and have been treated in a number of different ways. Two of the simplest and most successful ways to remove seborrheic keratoses are cryosurgery and curettage.

The investigators are conducting this study to see which of these two treatments has the best result.

Approximately 24-30 people will take part in this research study at the Hershey Medical Center.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 25
• Est. completion date: June 6, 2013
• Est. primary completion date: May 11, 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• have at least 1 seborrheic keratosis on each side of his/her trunk or proximal extremities.

• be able to understand the consent form and evaluation of treatment questionnaire.

Exclusion Criteria:

• Children <18 are excluded from this study based on their inability to independently complete the informed consent and research associated questionnaire.

Related Conditions & MeSH terms

• Keratosis
• Keratosis, Actinic
• Keratosis, Seborrheic
• Seborrheic Keratosis

Intervention

Procedure:
• cryosurgery
freezing of lesion with liquid nitrogen
• Curettage
the lesion will be anesthetized and destroyed with a curette.

Locations

Country	Name	City	State
United States	Penn State Milton S. Hershey Medical Center	Hershey	Pennsylvania

Sponsors (1)

Lead Sponsor	Collaborator
Milton S. Hershey Medical Center

Country where clinical trial is conducted

United States, 

References & Publications (2)

Brodsky J. Management of benign skin lesions commonly affecting the face: actinic keratosis, seborrheic keratosis, and rosacea. Curr Opin Otolaryngol Head Neck Surg. 2009 Aug;17(4):315-20. doi: 10.1097/MOO.0b013e32832d75e3. Review. — View Citation

Herron MD, Bowen AR, Krueger GG. Seborrheic keratoses: a study comparing the standard cryosurgery with topical calcipotriene, topical tazarotene, and topical imiquimod. Int J Dermatol. 2004 Apr;43(4):300-2. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Partial or complete resolution of treated lesion.	Follow up evaluation by a blinded physician along with the gathering of patient information via questionnaires will be obtained at the completion of the study.	6 weeks