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Pilot Study for the Use of Photodynamic Therapy in the Treatment of Seborrheic Dermatitis

Seborrheic Dermatitis Clinical Trial

Official title:
Pilot Study for the Use of Photodynamic Therapy in the Treatment of Seborrheic Dermatitis

Clinical Trial Summary

The purpose of this study is: 1. To determine the efficacy of photodynamic therapy (PDT) in the treatment of seborrheic dermatitis. 2. To determine how PDT alters the skin microbiome in subjects with seborrheic dermatitis before and after treatment. 3. To determine how PDT alters sebum secretion rates in subjects with seborrheic dermatitis before and after treatment. The researchers hypothesize that PDT will be efficacious in the treatment of seborrheic dermatitis.

Clinical Trial Description

This pilot project investigates the use of PDT may be useful in the treatment of seborrheic dermatitis based on the following: The Malassezia spp is capable of forming biofilms, 2) PDT has been shown to be effective against Malassezia spp PDT can break up bioflims of both bacterial and fungal origin and benzoyl peroxide, a prooxidant treatment similar to PDT, has been shown to be effective in the treatment of seborrheic dermatitis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03114111
Study type Interventional
Source University of California, Davis
Contact
Status Completed
Phase Early Phase 1
Start date January 2017
Completion date December 4, 2019
View Details
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