Psychological Factors That Influence Severity of Allergic Rhinitis

Status Completed

Clinical Trial Summary

Objective biomarker of allergic rhinitis severity is necessary for monitoring disease severity and response to treatment in clinical setting and for research. We believe that psychological factors are the missing link between patient-perceived severity of allergic rhinitis and objective biomarkers. In our pilot study, several psychological factors were studied in relation to patient reported outcomes for severity of allergic rhinitis.

Clinical Trial Description

Monitoring allergic rhinitis (AR) severity with objective biomarkers is important for the clinical management of patients as well as for research purposes. The most commonly used tool for the assessment of AR severity is the Total Nasal Symptom Score (TNSS). Objective biomarkers like skin prick test size or specific IgE levels don't correlate with TNSS. We studied skin prick test size and specific IgE and several patient reported outcomes including symptom score, medication scores, combined score and Juniper mini rhinitis quality of life questionnaire (RQLQ). Psychometric evaluation was performed using 5 different psychological questionnaires that measure 13 different psychological factors. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04709614
Study type	Observational
Source	The University Clinic of Pulmonary and Allergic Diseases Golnik
Contact
Status	Completed
Phase
Start date	January 1, 2016
Completion date	June 30, 2019

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