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Scoliosis Idiopathic clinical trials

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NCT ID: NCT06417944 Recruiting - Scoliosis Clinical Trials

The Effect of Three-dimensional Exercise (Schroth Exercise) on Diaphragm Thickness in Adolescent Idiopathic Scoliosis Patients

Start date: May 14, 2024
Phase:
Study type: Observational [Patient Registry]

Spinal deformity is common in childhood and adolescence, and can often present as scoliosis or increased thoracic kyphosis deformity with various etiologies.The diaphragm is the main respiratory muscle, and diaphragm contraction is associated with respiratory functions.Any spinal deformity, especially one that affects the thoracic spine, can affect lung function.In the planned thesis study, investigators will measure the diaphragm thickness in adolescent idiopathic scoliosis patients with scoliosis deformities affecting the thoracic region, whether there is any relationship between the impact in the thoracic region and the diaphragm thickness, and the three-dimensional exercise (Schroth exercise-Barcelona Schroth therapy) applied in investigators' clinic for scoliosis, before and after the treatment of the diaphragm. Investigators aimed to show whether there is any change in thickness.

NCT ID: NCT06408896 Active, not recruiting - Clinical trials for Scoliosis Idiopathic

Development and Internal Validation of Predicting Models of Idiopathic Scoliosis Natural History and Treatment Outcomes Through the Use of Artificial Intelligence in a Large Clinical Database

PREPARE
Start date: April 24, 2024
Phase:
Study type: Observational

Scoliosis is a three-dimensional deformity of the spine. In its most common form (about 70% of cases), the causes are unknown, therefore it is called idiopathic scoliosis. In most cases, it is discovered after 10 years of age, and is defined diagnostically as a curve of at least 10°, measured on a standing x-ray using the Cobb method. If scoliosis exceeds the critical threshold of 30° Cobb at the end of growth, there is a progressively greater risk of health and social problems in adult life. For this reason, the main aim of the treatment is to complete the growth period with a curve less than 30° and good sagittal balance, or at least well below 50°, which represents the surgical threshold. Growth is a factor favouring the evolution of deformities, therefore patients are followed until the end of growth. This is why therapy can last many years, from the discovery of the presence of a deformity until bone maturation is achieved. The early identification of parameters predictive of the outcome of the therapy to direct the least possible aggressiveness towards the result necessary for the patient's future, integrated with the evaluation of its effectiveness (monitoring), is one of the most important objectives in this field to minimize the burden of treatment in a particular phase of growth such as adolescent development, as well as to identify the subjects most at risk of worsening in adulthood. The systematic collection of clinical data during the therapeutic process offers the possibility, through advanced analysis models, applied retrospectively, to identify predisposing factors and protective factors. When the data available is sufficiently large, it is possible to obtain predictive equations that assist clinicians in therapeutic choices and help patients understand the risks and benefits of available therapies. New technologies such as artificial intelligence techniques offer new and interesting ways of estimating risks and calculating the benefits and safety of some therapeutic choices compared to others. This study aims to develop and internally validate data-driven stratification and prediction models to predict multiple end-of-care outcome measures that include curve magnitude, measured in Cobb degrees, measures determining the sagittal balance, and measures of quality of life and function measured through self-completion questionnaires.

NCT ID: NCT06356350 Recruiting - Clinical trials for Juvenile Idiopathic Arthritis

Exercise Programs on Gait in Children With Scoliosis Diagnosed JIA

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

Juvenile Idiopathic Arthritis (JIA) is one of the common chronic diseases in childhood. Problems such as weakness or pain may occur in JIA, especially in the joints and the muscles around the trunk (1). These conditions may lead to abnormal displacement of the center of gravity, deterioration of biomechanics, and muscle imbalance in children with JIA (2, 3). All these situations can lead to scoliosis, which we often encounter in children with JIA. Current studies describing various 3-dimension (3D) exercise methods (SEAS, Schroth, Dobomed, BSPTS, Side-shift, Lyon, etc.) effective on scoliosis (4). However, no study was found in the literature that searching the effects of these exercise methods on gait parameters in children with scoliosis diagnosed JIA.

NCT ID: NCT06347419 Not yet recruiting - Clinical trials for Scoliosis Idiopathic

Body Awareness and Spinal Stability in Scoliosis

Start date: April 30, 2024
Phase:
Study type: Observational

Thirty volunteer patients diagnosed with scoliosis by a specialist physician at Gazi University Hospital Orthopedics and Traumatology Department and subsequently referred to Gazi University Physiotherapy and Rehabilitation Department for exercise training will be included in the study. The lumbar Pressure Measurement Test with Stabilizer and Rotation Stability Tests will be utilized to evaluate the spinal stability of the patients. Body awareness will be assessed using the Body Awareness Survey, comprising 18 questions. All assessments will be conducted at the Orthopedic Rehabilitation Clinic within the relevant department. The results obtained from this study will elucidate the relationship between body awareness and spinal stability in individuals with scoliosis.

NCT ID: NCT06341465 Not yet recruiting - Scoliosis Clinical Trials

Investigation of the Effects of Exercise and Kinesiological Taping on Spinal Deformities and Serum Markers in Individuals With Scoliosis

Start date: April 4, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effects of Schroth exercises and kinesiological taping on spinal deformities and serum markers in young adults with scoliosis. The study will include young adults aged 18-21 with scoliosis. A total of 57 participants will be included in the study. Out of 57 participants, 38 have scoliosis, and 19 are healthy. 38 participants will be randomly divided into 2 groups. One group (n=19) will receive only Schroth exercises, and the other group (n=19) will receive both Schroth exercises and kinesiological taping. The laboratory analyses of proteins associated with autophagy (Beclin-1, LC3, and ATG3) and bone-cartilage metabolism (COMP and MMP-3) will be conducted in the Biomedical Engineering Laboratory of our university. Trunk rotation will be assessed using the Adams Forward Bend Test with scoliometer, quality of life will be evaluated with the SRS-22 Quality of Life questionnaire and Quality of life profile for spinal deformities questionnaire, perception of deformity will be measured using the Walter Reed Visual Assessment Scale, and Cobb angles will be evaluated from anterior-posterior X-ray images.

NCT ID: NCT06266637 Active, not recruiting - Clinical trials for Scoliosis Idiopathic

Effect of Scoliosis-Specific Exercise on Lower Limb Biomechanics

Start date: March 12, 2023
Phase: N/A
Study type: Interventional

PURPOSE: To examine the effect of Physiotherapeutic Scoliosis-Specific Exercise on limb biomechanical parameters in adolescents with idiopathic scoliosis. A randomised controlled trial BACKGROUND: Adolescent idiopathic scoliosis is one of the most common orthopaedic diseases affecting the spine during adolescence. The efficacy of exercise treatment is controversial. Although evidence suggests that PSSE, which include auto-correction in 3D, integration in daily life, stabilizing the corrected posture, and patient education, could improve some outcomes, effect of PSSE on related biomechanical alterations in lower limbs have not yet been examined. HYPOTHESES: Null hypothesis There are no statistically significant effect of Physiotherapeutic Scoliosis-Specific Exercise on lower limb biomechanics in scoliotic adolescents. RESEARCH QUESTION: What are the effect of Physiotherapeutic Scoliosis-Specific Exercise on lower limb biomechanics in scoliotic adolescents.?

NCT ID: NCT06242821 Not yet recruiting - Scoliosis Clinical Trials

Back Pain Management in AIS: Yoga vs Physical Therapy

AIS
Start date: May 2024
Phase: N/A
Study type: Interventional

Targeting non-operative Adolescent Idiopathic Scoliosis (AIS) patients, including those who are braced and non-braced, this research project at Johns Hopkins Hospital seeks to revolutionize the treatment approach for Adolescent Idiopathic Scoliosis. This innovative study compares traditional physical therapy with a yoga-based intervention, focusing on alleviating back pain and enhancing quality of life in this specific patient group. This research is anchored in substantial existing evidence that highlights the physiological and psychological benefits of yoga and is in alignment with current AIS treatment strategies. Addressing the urgent need for diverse non-operative management strategies for AIS, this study is particularly timely given the challenges in accessing physical therapy and the growing concerns over opioid use. The investigators exploration of structured yoga protocols aims to introduce a viable alternative therapy, providing significant relief and improving the quality of life for AIS patients who are not candidates for surgery. By integrating cutting-edge healthcare solutions with the increasing interest in yoga in the U.S., this project aims to establish a new benchmark in non-surgical AIS treatment that is both effective and accessible to a wide range of patients

NCT ID: NCT06093477 Not yet recruiting - Spondylolisthesis Clinical Trials

Studying Melatonin and Recovery in Teens

SurgerySMART
Start date: July 2024
Phase: N/A
Study type: Interventional

The goal of this feasibility clinical trial is to learn if melatonin can help teens having spinal fusion surgery by promoting healthy sleep. Melatonin is available as a dietary supplement that may be effective in promoting longer, higher quality sleep. This study will assess the feasibility and acceptability of melatonin for teens undergoing spinal fusion surgery, as well as determine optimal measured outcomes (sleep, pain, health-related quality of life) at short- and long-term follow-up.

NCT ID: NCT06086431 Recruiting - Clinical trials for Scoliosis Idiopathic

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Pediatric Idiopathic Scoliosis Surgery

Start date: October 17, 2023
Phase: Phase 4
Study type: Interventional

Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for pediatric, idiopathic scoliosis surgery.

NCT ID: NCT06063447 Completed - Clinical trials for Pelvic Floor Disorders

Does Adolescent Idıopathic Scoliosis Cause Pelvic Floor Dysfunction?

Start date: May 2, 2023
Phase:
Study type: Observational [Patient Registry]

The aim of this study was to investigate relationship between the type and severity of scoliosis and pelvic floor dysfunctions in individuals with adolescent idiopathic scoliosis.