Scleroderma Clinical Trial
Official title:
Probiotics in Patients With Moderate-to-severe Distention/ Bloating From Systemic Sclerosis
Organs of the gastrointestinal tract include the mouth, throat, stomach, intestines, and
anus. Patients with scleroderma often have GIT disorders. GIT disorders can be severely
debilitating and even life-threatening. Some problems associated with GIT disorders may
include heartburn, loss of voice or hoarseness, ulcers (open sores), difficulty swallowing,
constipation, diarrhea, malabsorption (impaired absorption of nutrients from the GI tract),
diminished peristalsis (decreased in the wavelike motion in the muscles of the intestines),
and the inability to control your bowel movements.
Probiotics are the "good bacteria" normally found in your digestive tract. Our group is
looking at whether or not taking daily probiotics (lactobacillus) can help alleviate some of
these symptoms in scleroderma patients that have GIT disorders.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
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