Clinical Trials Logo
  1. Home
  2. SCID
  3. NCT01652092

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies

Chronic Granulomatous Disease Clinical Trial

Official title:
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies

Clinical Trial Summary

This is a standard of care treatment guideline for allogeneic hematopoetic stem cell transplant (HSCT) in patients with primary immune deficiencies.

Clinical Trial Description

Based on diagnosis and clinical history, a determination of the most appropriate regimen will be made based on the following prep plans: Arm A: Fully Myeloablative Preparative Regimen, Arm B: Reduced Toxicity Ablative Preparative Regimen, Arm C: Reduced Intensity Conditioning, Arm D: No Preparative Regimen ;

Study Design

Related Conditions & MeSH terms

  • Bare Lymphocyte Syndrome
  • CD40 Ligand Deficiency
  • Chediak-Higashi Syndrome
  • Chronic Granulomatous Disease
  • Common Variable Immunodeficiency
  • Granulomatous Disease, Chronic
  • Griscelli Syndrome
  • Hemophagocytic Lymphohistiocytosis
  • Histiocytosis
  • Histiocytosis, Langerhans-Cell
  • Hyper IgM Syndrome
  • Immunologic Deficiency Syndromes
  • Langerhan's Cell Histiocytosis
  • Lymphohistiocytosis, Hemophagocytic
  • Lymphoproliferative Disorders
  • Omenn's Syndrome
  • Primary Immunodeficiency Diseases
  • Reticular Dysgenesis
  • SCID
  • Severe Combined Immunodeficiency
  • Syndrome
  • Wiskott-Aldrich Syndrome
  • X-linked Lymphoproliferative Disease
Clinical Trial Details
NCT number NCT01652092
Study type Interventional
Source Masonic Cancer Center, University of Minnesota
Contact Christen Ebens, MD
Phone 612-626-2778
Email ebens012@umn.edu
Status Recruiting
Phase N/A
Start date September 4, 2012
Completion date December 2026
View Details
See also
  Status Clinical Trial Phase
Withdrawn NCT03278912 - Natural History of Intestinal Inflammation in People With Primary Immune Dysregulations
Completed NCT04136028 - IL-1 Receptor Inhibitor for Granulomatous Complications in Patients With Chronic Granulomatous Disease Early Phase 1
Recruiting NCT05687474 - Baby Detect : Genomic Newborn Screening
Terminated NCT03080480 - Pioglitazone Therapy for Chronic Granulomatous Disease Phase 1/Phase 2
Terminated NCT00394316 - Gene Therapy for Chronic Granulomatous Disease Early Phase 1
Recruiting NCT03910452 - Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide Early Phase 1
Terminated NCT02282904 - Haploidentical Transplant for People With Chronic Granulomatous Disease Using Post Transplant Cyclophosphamide Phase 1/Phase 2
Terminated NCT02926963 - Generation of Powerful Biological Tools for Understanding the Pathophysiology of Chronic Granulomatous Disease. N/A
Completed NCT00006417 - Modified Stem Cell Transplantation Procedure for Treating Chronic Granulomatous Disease Phase 2
Completed NCT00368446 - Genetic Disorders of Mucociliary Clearance in Nontuberculous Mycobacterial Lung Disease
Enrolling by invitation NCT03655223 - Early Check: Expanded Screening in Newborns
Recruiting NCT06162936 - Neutrophil Oxidative Burst in Early and Late Onset Pediatric Inflammatory Bowel Disease
Terminated NCT05915897 - Whole Blood Biospecimen Collection for Subjects With Chronic Granulomatous Disease (CGD)
Terminated NCT00325078 - Infliximab to Treat Crohn'S-like Inflammatory Bowel Disease in Chronic Granulomatous Disease Phase 1/Phase 2
Completed NCT00001317 - A Phase IV Study of Recombinant Human Gamma Interferon in Patients With Chronic Granulomatous Diseases of Childhood Phase 4
Completed NCT03548818 - Role of Interferon-gamma 1-b (IFN-γ) on Cells of the Innate Immune System: Functional, Biochemical and Gene Expression Studies in Patients With Chronic Granulomatous Disease
Recruiting NCT01821781 - Immune Disorder HSCT Protocol Phase 2
Completed NCT00578643 - Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous Disease Phase 2
Terminated NCT00006054 - Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies N/A
Enrolling by invitation NCT06253507 - pCCLCHIM-p47 (Lentiviral Vector Transduced CD34 Plus Cells) in Patients With p47 Autosomal Recessive Chronic Granulomatous Disease (AR-CGD) Phase 1/Phase 2