Schizophrenic Patients Clinical Trial
| NCT number | NCT01550211 |
| Other study ID # | SHA-0001-12 |
| Secondary ID | |
| Status | Not yet recruiting |
| Phase | N/A |
| First received | March 7, 2012 |
| Last updated | March 7, 2012 |
| Start date | March 2012 |
This study aims to identify electrophysiological correlates of impaired perceptual and
linguistic processes in chronic schizophrenic patients, un-medicated first-episode
schizophrenic patients and their healthy relatives.
Following administrating some questionnaires (demographic details and psychiatric history
questionnaire, handedness questionnaire, reading abilities test and positive and negative
symptoms questionnaire) and performing a perception test and a verbal abstract intelligence
test, participants will conduct a brain scan during a series of perceptual and linguistic
tasks.
| Status | Not yet recruiting |
| Enrollment | 150 |
| Est. completion date | |
| Est. primary completion date | March 2014 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | Both |
| Age group | 18 Years to 65 Years |
| Eligibility |
Inclusion Criteria: Inclusion criteria for chronic patients: - Hebrew native speakers. - Diagnosis of schizophrenia with a history of more than one episode. - Capable and willing to provide informed consent. Inclusion criteria for naive patients: - Hebrew native speakers. - Diagnosis of schizophrenia with a history of only one episode and unmedicated. - Capable and willing to provide informed consent. Inclusion criteria for patients' relatives (control group 1): - Hebrew native speakers. - Without any psychiatric history. - Have a child and/or a sibling with schizophrenia. Inclusion Criteria for students (control group 2): - Hebrew native speakers. - Without any psychiatric history. Exclusion Criteria: Exclusion Criteria for patient groups (chronic and "naïve"): - Left handedness. - Reading disability. - Visual perception disability. - Brain damage and/or a history of seizures. - Impaired intelligence. - Metal implants. Exclusion Criteria for control groups (family members and students): - Psychiatric history. - Left handedness. - Reading disability. - Visual perception disability. - Brain damage and/or a history of seizures. - Impaired intelligence. - Metal implants. |
Observational Model: Case Control, Time Perspective: Prospective
| Country | Name | City | State |
|---|---|---|---|
| Israel | Shalvata MHC | Hod-Hasharon |
| Lead Sponsor | Collaborator |
|---|---|
| Shalvata Mental Health Center | Bar-Ilan University, Israel |
Israel,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Magnetic field amplitude and source | 45 minutes | No |