Impact of General Anaesthetics on Excitability of the Peripheral Sensory Nerve

Scheduled for Surgery Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00696254
• Other study ID #: 5-2008
• Status: Completed
• Phase: Phase 1
• First received: March 17, 2008
• Last updated: June 2, 2009
• Start date: March 2008
• Est. completion date: December 2008

Study information

• Verified date: June 2009
• Source: University of Zurich
• Contact: n/a
• Is FDA regulated: No
• Health authority: Switzerland: UZurich
• Study type: Observational

Clinical Trial Summary

The aim of this study is to investigate the effect of general anaesthetics on nerve excitability. We use the method of threshold tracking to measure selected parameters of nerve excitability.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 0
• Est. completion date: December 2008
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 75 Years

Eligibility

Inclusion criteria: German speaking patients scheduled for surgery under general anaesthesia.

Weight 50 - 100 kg signed informed consent

Exclusion criteria: 1. known peripheral neuropathy 2. Diabetes mellitus 3. Neuro-psychiatric Diagnosis 4. pregnant/ breast-feeding women 5. congestive heart disease

6. more than 2 risk factors (out of 4) for PONV (female, non-smoker, known PONV, opioids postoperatively) 7. participants of other studies 8. inability of verbal expression

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Scheduled for Surgery

Intervention

Behavioral:
• Nerve excitability measurement

Locations

Country	Name	City	State
Switzerland	University Hospital Zurich	Zurich

Sponsors (1)

Lead Sponsor	Collaborator
University of Zurich

Country where clinical trial is conducted

Switzerland,