Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to find out what effects the combination of Nivolumab and Pemetrexed has on you and your cancer. The safety of this combination and the effectiveness of this treatment will be studied.


Clinical Trial Description

The treatment of patients with SCCHN is challenging, and represents an area of high unmet need. Treatment options within this patient population are limited, and inadequately treated disease may cause high morbidity, negatively impacting quality of life and leading to increased costs for supportive care. To address the unmet needs of these patients, this exploratory trial combining pemetrexed with standard-of-care nivolumab, with an investigational plan to study clinical and health services outcomes is being proposed. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04107103
Study type Interventional
Source AHS Cancer Control Alberta
Contact
Status Completed
Phase Phase 2
Start date March 19, 2020
Completion date April 28, 2023

See also
  Status Clinical Trial Phase
Not yet recruiting NCT04595981 - Chemo-embolization for Head and Neck Cancer Phase 2
Enrolling by invitation NCT01393184 - Safety and Efficacy Study of Target Therapy Combined With Radiotherapy to Treat Senile Locally Advanced SCCHN Phase 2
Recruiting NCT04925284 - Study of XB002 in Subjects With Solid Tumors (JEWEL-101) Phase 1
Recruiting NCT03771820 - Combination Therapy With NC-6004 and Pembrolizumab in Head and Neck Cancer Subjects Who Have Failed Platinum Regimen Phase 2
Recruiting NCT02878655 - Evaluation of the Overall Quality of Life After the Neck Dissection Retro-spinal Sector (IIb), in Squamous Cell Carcinomas Clinical and Radiological N0 VADS
Completed NCT02573259 - A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors Phase 1