Scar Tissue or Healthy Skin Clinical Trial
Official title:
Measurement and Comparison of the Occlusive and Hydrating Capacity of Three Silicone Gels: BAP Scar Gel, Dermatix, Kelocote and One Gel- Cream: Alhydran
Study hypothesis: Is Alhydran gel-cream as efficient as silicone gel for skin occlusion and
hydration?
For this study 16 volunteers and ten patients with healed full thickness burns will be
included.
After a short period of acclimatization four test areas will be determined. For healthy
volunteers the standard zones are located on the inner forearm, two on each forearm.
For patients with healed burns the 4 test zones are located on either the healed donor site
or the healed skin grafted area.
In each test zone baseline measurements will be taken before application of the
products.After application of the three silicone gels and the hydrating gel cream the trans
epidermal water loss (TEWL) and the moisture content of the stratum corneum will be measured
by using the TEWAmeter®TM300 and the Corneometer® CM825 (Courage & Khazaka).
n/a
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment