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Anti COVID-19 Antibodies in Follicular Fluid and Spermatic Fluid

SARS-CoV-2 Clinical Trial

Official title:
Anti COVID-19 Antibodies in Spermatic Fluid and Follicular Fluid

Clinical Trial Summary

Patients going through an in vitro fertilization cycle will be asked to participate . Patients will be asked for their COVID-19 exposure : post confirmed disease/post vaccine/not exposed to disease or vaccine . Patients will provide the fluids which are not required , once fertilization process is completed. Patients will also provide 5ml blood sample by the day of procedure. Anti COVID-19 immunoglobulin G type antibodies will be measured in all samples . Data regarding age, date of infection/vaccine will be collected . Progesterone and Estrogen will be measured in female patients' samples and Perlecan level will be measured in follicular fluid.

Clinical Trial Description

Patients going through an in vitro fertilization cycle will be asked to participate . Patients will be asked for their COVID-19 exposure : post confirmed disease/post vaccine/not exposed to disease or vaccine . Patients will provide the fluids which are not required in the day of egg retrieval : the follicular fluid remaining after isolation of the egg and spermatic fluid only, if not utilized for fertilization. The fluids will be collected once fertilization process is completed. Patients will also provide 5ml blood sample by the day of procedure. Anti COVID-19 immunoglobulin G type antibodies will be measured in all samples . Data regarding age, date of infection/vaccine will be collected as well as indication for treatment, Estradiol level before the egg retrieval, number of eggs collected and the triggering ovulation modality . Progesterone and Estrogen will be measured in female patients' samples (follicular fluid and serum). Perlecan level will be measured in follicular fluid. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04822012
Study type Observational
Source Meir Medical Center
Contact Daniela Hoffman
Phone +97226777242
Email danielho@hadassah.org.il
Status Recruiting
Phase
Start date March 1, 2021
Completion date June 1, 2021
View Details
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