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Clinical Trial Summary

This study aims to quantify and follow the cumulative incidence of SARS-CoV-2 infection in the French population using serological tests and to assess the determinants of infection from Constances, E3N-E4N, ELFE-Epipage 2 and NutriNet-Santé cohorts.


Clinical Trial Description

The primary objective is to assess the cumulative incidence of infection in the general population using dried blood spot sampling. The secondary objectives are: - To identify factors associated with a positive SARS-CoV-2 infection (positive serology) and to characterize the durability of the serological response to SARS-CoV-2 - To identify associations of symptoms predictive of a SARS-CoV-2 infection - To estimate the health care use associated with a SARS-CoV-2 infection - To estimate the fraction of sub-clinical infections or infections not captured by the healthcare system; - To study the acceptability of a mass anti-SARS-CoV-2 serological testing and the impact of its result, linked with social inequalities in health; - To estimate the individual and collective impact of containment and other preventive measures on the risk of SARS-CoV-2 infection; - To study the impact of social and territorial inequalities on seroprevalence levels. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04392388
Study type Observational
Source Institut National de la Santé Et de la Recherche Médicale, France
Contact
Status Completed
Phase
Start date May 1, 2020
Completion date April 11, 2023

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