Clinical Trials Logo

SARS-CoV-2 PCR Test Positive clinical trials

View clinical trials related to SARS-CoV-2 PCR Test Positive.

Filter by:
  • Completed  
  • Page 1

NCT ID: NCT04681430 Completed - Clinical trials for SARS-CoV-2 Infection

Reconvalescent Plasma/Camostat Mesylate Early in SARS-CoV-2 Q-PCR (COVID-19) Positive High-risk Individuals

RES-Q-HR
Start date: January 8, 2021
Phase: Phase 2
Study type: Interventional

This study is a 4-arm, multicenter, randomized, partly double- blind, controlled trial to evaluate the safety and efficacy of convalescent serum (CP) or camostat mesylate with control or placebo in adult patients diagnosed with SARS-CoV-2 and high risk for moderate/severe COVID-19. The working hypothesis to be tested in the RES-Q-HR study is that the early use of convalescent plasma (CP) or camostat mesylate (Foipan®) reduces the likelihood of disease progression to modified WHO stages 4b-8 in SARS-CoV-2 positive adult patients at high risk of moderate or severe COVID-19 progression. The primary endpoint of the study is the cumulative number of individuals who progressed to or beyond category 4b on the modified WHO (World Health Organization) COVID-19 ordinal scale within 28 days after randomization.