SARS-CoV-2 Infection Clinical Trial
Official title:
Breath Analysis for SARS-CoV-2 in Infected and Healthy Subjects
Recently published studies could demonstrate that detection of specific biomarkers in breath could be applied for the diagnosis of SARS-CoV-2.
In this study we want to address the sensitivity and specificity of breath analysis by
MCC-IMS in the context of SARS-CoV-2 detection from PCR- proven infected and non-infected
subjects.
Therefore nasal breath will be aspirated for 10 seconds during normal respiration by a foam
cuffed oxygen catheter connected via a 0.22μm filter and a line into the MCC-IMS and directly
analyzed without any pre-analytic procedures.
The during the proof-of-concept study derived significant peaks for volatile organic
compounds will be used for discrimination in a point-of-care approach.
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